魏伟，黄色仓库
教授，硕士生导师，中科院成都生物研究所药物化学博士，加拿大麦吉尔大学（McGill University）博士后（合作导师李朝军院士），山东省优秀青年人才基金获得者（省优青）, 山东省高校“青创科技计划”绿色化学团队学术带头人，入选黄色仓库
“1361”人才工程第二层次，杏坛学者。担任Chin. Chem. Lett 编委; Chin. J. Org. Chem青年编委。2023年被授予Chin. Chem. Lett.学术新星奖。2020-2024年连续5年入选世界前2%科学家名单。
科研方面：
近年来一直致力于有机化学和药物化学方面的研究工作。主持国家自然科学基金；山东省优秀青年人才基金（省优青）；山东省高校“青创科技计划”项目；山东省面上基金，青海省科技国际合作项目等多项基金；目前发表SCI论文130余篇，其中在Angew. Chem. Int. Ed, Chemical Science, Green Chemistry（8篇）, Chin. Chem. Lett.（10篇）, Organic Letters（5篇）, Chem Commun（4篇）, Org. Chem. Front.（11篇）, J. Org. Chem.（10篇）等国际知名学术杂志上发表第一或通讯作者SCI论文80余篇（SCI二区以上论文52篇），总引用6776余次。 4篇代表性论文是2025年全球本学科ESI前1%高被引top论文。2017年获山东省高等学校科学技术奖一等奖（首位）《具有抗癌等重要生物活性有机医药材料的绿色构筑研究》；2019年获得山东省自然科学奖二等奖（第二位）《具有抗肿瘤等生物活性药物中间体的绿色构建》，2020年获山东省高等学校科学技术奖二等奖（首位）《含硫医药材料的绿色构建》。授权国家发明专利20余项，其中转让发明专利5项。
教学情况：获得全国微课教学比赛三等奖1项，山东省微课教学比赛一等奖1项，主讲《有机化学》,《有机化学实验》,《中级有机化学实验》等课程；主持完成黄色仓库
精品实验 1 项，指导国家级大学生创新创业项目 2 项，指导学生在 2017和 2018 连续两年获得山东省优秀学士毕业论文。2017 年获黄色仓库
教学建设成果奖二等奖（首位），获奖课题：《有机化学课程体系优化与创新型人才培养探索》。
药物研发方面：2008-2012年 成都地奥集团药物研究所 药物研发实习研究员。在成都地奥集团提供的平台下，参与完成肿瘤辅助治疗药物阿瑞匹坦生产工艺、质量标准系统研究，项目得到“重大新药创制”国家科技重大专项的资助。参与完成抗癌药物卡陪他滨合成路线设计、工艺研究、中试放大和制剂等方面的研究。参与完成牛磺熊去氧胆酸的合成路线设计、工艺研究、中试放大方面的研究。设计合成的吡啶硫脲类杂环化合物，对肿瘤细胞和血管内皮细胞的增殖抑制作用活性优于抗癌药物索拉菲尼和瑞戈非尼，有望进一步开发出一种高活性的新型抗癌活性药物。
代表性奖励情况：
2013 年获全国高校微课教学比赛三等奖（个人）；
2013 年获山东省高校微课教学比赛一等奖（个人），
2014 年获山东省高等学校优秀科研成果奖三等奖（首位）；
2014 年获山东省自然科学学术创新二等奖（首位）；
2015 年获山东省高等学校优秀科研成果奖三等奖（第二位）；
2017 年获山东省高等学校科学技术奖一等奖（首位）
2017 年获得山东省优秀学士毕业论文指导老师（个人）；
2017 年获黄色仓库
优秀研究生指导老师（个人）。
2017 年获黄色仓库
教学建设成果奖二等奖（首位）
2018 年被评为黄色仓库
“先进科研工作者”（个人）
2018 年获黄色仓库
优秀研究生指导老师（个人）
2018 年获山东省优秀学士毕业论文指导老师（个人）
2019 年获黄色仓库
优秀研究生指导老师（个人）
2019 年获山东省自然科学奖二等奖（第二位）
2020 年获黄色仓库
优秀硕士毕业论文指导老师（个人）
2020 年获黄色仓库
优秀研究生指导老师（个人）
2020年山东省高等学校科学技术奖二等奖（首位）
2021 年山东省优秀硕士毕业论文指导老师（个人）
2022 年获黄色仓库
优秀研究生指导老师（个人）
2024年获黄色仓库
优秀研究生指导老师（个人）
在研究生培养方面，多位同学获得了研究生国家奖学金，并分别通过博士考核制进入中国科学院化学所、武汉大学、天津大学、中国人民大学读博。其中毕业同学已开启高校教职工作。指导的研究生多人次获得学校“圣地英才”奖、一等/二等奖学金等。
欢迎有科研追求的本科生、硕士生加入本研究团队，每年招收不低于2名研究生（专业：有机化学、材料与化工），择优推荐到985/211或中科院攻读博士学位。每届招收不高于8名本科毕业论文同学，2-5名优秀本科生进入团队开展科研训练工作。
★联系方式：
E-mail: [email protected], 科研室：实验中心B区624、626。
qq:471068894
代表性论文：
[1] Jindong Hao, Yufen Lv, Shuyue Tian, Chao Ma, Wenxiu Cui, Huilan Yue, Wei Wei∗, Dong Yi,∗Additive-free synthesis of β-keto phosphorodithioates via geminal hydro-phosphorodithiolation of sulfoxonium ylides with P4S10 and alcohols, Chin. Chem. Lett. 2024, 35, 109513.SCI一区
[2] Xiao-ming Chen, Jian Huang, Jun Pan, Yi Xie, Fei Zeng, Wei Wei,* and Dong Yi*, Construction of β‑Oximino Phosphorodithioates via (2,2,6,6- Tetramethylpiperidin-1-yl)oxyl-Promoted Difunctionalization of Alkenes with tert-Butyl Nitrite, P4S10, and Alcohols, Org. Lett. 2024, 26, 3883−3888.SCI一区,
[3] Jian Huang, Chao Ma, Jian Sun, Wenhui Gao, Yufen Lv, Huilan Yue, Dong Yi, and Wei Wei*，Oxyphosphorodithiolation of Vinyl Azides with P4S10 and Alcohols Leading to β‑Keto Phosphorodithioates，J. Org. Chem. 2024, 89, 18384−18392。
[4] Yufen Lv, Hongyu Dinga, Jinmao You, Wei Wei∗, Dong Yi∗, Additive-free synthesis of S-substituted isothioureas via visible-light-induced four-component reaction of α-diazoesters, aryl isothiocyanates, amines and cyclic ethers, Chin. Chem. Lett. 2024, 35, 109107.SCI一区, IF=9.1
[5] Chengming Qu, Yalu Wang, Yufen Lv, Huilan Yue, Wei Wei* and Dong Yi*，Metal-free hydrophosphorodithiolation of alkynes with P4S10 and alcohols leading to vinyl phosphorodithioates，Org. Chem. Front., 2024, 11, 171–175.SCI一区, IF=5.4
[6] Zhiwei Wang, Na Meng, Yufen Lv, Wei Wei,* Huilan Yue,* Guofu Zhong, Photocatalyst-free visible-light-mediated three-component reaction of α-diazoesters, cyclic ethers and NaSCN to access organic thiocyanates, Chin. Chem. Lett. 2023, 34, 107599.SCI一区IF=9.1
[7] Chengming Qu, Yufen Lv, Jian Huang, Chao Ma, Huilan Yue, Wei Wei * and Dong Yi*，Additive-free aerobic oxidative difunctionalization of alkenes with P4S10 and alcohols to access β-hydroxy phosphorodithioates，Green Chem., 2023, 25, 10678–10683.SCI一区, IF=9.8
[8] Hongyu Ding, Zhiwei Wang, Chengming Qu, Yufen Lv, Xiaohui Zhao and Wei Wei∗, Visible-light-mediated multi-component carbene transfer reactions of α-diazoesters to construct multisubstituted pyrazoles and 1,3-dicarbonyl derivatives, Org. Chem. Front., 2022, 9, 5530–5535. SCI一区IF=5.456
[9] Hongyu Ding, Siyu Shi, Yanan Hou, Wenxiu Cui, Rong Sun, Yufen Lv,* Huilan Yue, Wei Wei,*and Dong Yi*, Visible-Light-Promoted Cascade Coupling of 2- Isocyanonaphthalenes with Elemental Sulfur and Amines to Construct Naphtho[2,1-d]thiazol-2-Amines, Chem. Eur. J. 2024, 30, e202400719.SCI二区, IF=3.9
[10] Lianhui Song, Chao Ma, Jian Huang, Yufen Lv, Huilan Yue, Jinmao You,* Wei Wei,* and Dong Yi*, Visible-Light Photoredox-Catalyzed Difunctionalization of Alkynes with Quinoxalin-2(1H)‑Ones, P4S10, and Alcohols, J. Org. Chem. 2024, 89, 10974−10986.SCI二区, IF=4.3
[11] Yufen Lv, Zhiwei Wang, Lianhui Song, Jindong Hao, Shuyun Zhu, Huilan Yue, Wei Wei,* and Dong Yi*，Copper-Catalyzed Three-Component Tandem Reaction of Alkynes, α‑Diazo Esters, and TMSN3 to Access N‑Substituted 1,2,3-Triazoles，J. Org. Chem. 2023, 88, 17266−17273.SCI二区, IF=4.2
[12] Chengming Qu, Jindong Hao, Hongyu Ding, Yufen lv, Xian-En Zhao, Xiaohui Zhao, and Wei Wei,* Visible-Light-Initiated Multicomponent Reactions of α‑Diazoesters to Access Organophosphorus Compounds, J. Org. Chem. 2022, 87, 12921−12931SCI 二区topIF=4.83
[13] Chengming Qu, Ruisheng Liu, Zhiwei Wang, Yufen Lv, Huilan Yue* and Wei Wei*, Visible-light-driven multicomponent reactions to access S-alkyl phosphorothioates using elemental sulfur as the sulfur source, Green Chem., 2022, 24, 4915–4920. SCI一区IF=9.8.
[14] Zhiwei Wang, Qishun Liu, Ruisheng Liu, Zhongyin Ji, Yan Li, Xiaohui Zhao, Wei Wei,* Visible-light-initiated 4CzIPN catalyzed multi-component tandem reactions to assemble sulfonated quinoxalin-2(1H)-ones, Chin. Chem. Lett. 2022, 33, 1479–1482，SCI一区IF=9.1
[15] Zhiwei Wang, Ruisheng Liu, Chengming Qu, Xian-En Zhao, Yufen Lv,* Huilan Yue * and Wei Wei,*Elemental sulfur as the “S” source: visible-lightmediated four-component reactions leading to thiocyanates, Org. Chem. Front., 2022, 9, 3565–3570. SCI一区IF=5.456
[16] Qishun Liu,# Leilei Wang,# Huilan Yue, Jiang-Sheng Li, Zidan Luo and Wei Wei,* Catalyst-free visible-light-initiated oxidative coupling of aryldiazo sulfones with thiols leading to unsymmetrical sulfoxides in air, Green Chem. 2019, 21, 1609–1613. SCI一区IF=11.034.
[17] Yufen Lv,# Pengli Bao,# Huilan Yue,* Jiang-Sheng Li and Wei Wei,* Visible-light-mediated metal-fe decarboxylative acylations of isocyanides with α-oxocarboxylic acids and water leading to α-ketoamides, Green Chem. 2019, 21, 6051–6055. SCI一区IF=11.034.
[18] Wei Wei,* Huanhuan Cui, Huilan Yue* and Daoshan Yang*, Visible-light-enabled oxyazidation of alkenes leading to α-azidoketones in air. Green Chem. 2018, 20, 3197–3202. SCI一区IF=11.034.
[19] Wei Wei,* Huanhuan Cui, Daoshan Yang, Huilan Yue, Chenglong He, Yulong Zhang, Hua Wang,* Visible-light-enabled spirocyclization of alkynes leading to 3-sulfonyland 3-sulfenyl azaspiro[4,5]trienones, Green Chem. 2017, 19, 5608–5613.SCI一区IF=11.034.
[20] Huanhuan Cui, Wei Wei,* Daoshan Yang, Yulong Zhang, Huijuan Zhao, Leilei Wang and Hua Wang*,Visible-light-induced selective synthesis of sulfoxides from alkenes and thiols using air as the oxidant. Green Chem, 2017, 19, 3520-3524.SCI一区IF=11.034.
[21] Wei Wei, Xi-Jie Dai, Haining Wang, Chenchen Li, Xiaobo Yang and Chao-Jun Li*, Ruthenium(II)-catalyzed olefination via carbonyl reductive cross-coupling, Chemical Science, 2017, 8, 8193-8197. SCI 一区 IF=9.346
[22] Wei Wei，Jian-Xin Ji *, Catalytic and Direct Oxyphosphorylation of Alkenes with Dioxygen and H-Phosphonates Leading to b-Ketophosphonates, Angew. Chem. Int. Ed., 2011, 50, 9097-9099 . SCI 一区 IF = 13.1
[23] F. Zhao, N. Meng, T.Sun, J.Wen, X. Zhao and W. Wei, Metal-free electrochemical synthesis ofα-ketoamides via decarboxylative coupling of α-keto acids with isocyanides and water, Org. Chem. Front., 2021, 8, 6508-6514.SCI 一区IF=5.456
[24] Pengli Bao, Fei Liu, Yufen Lv, Huilan Yue,* Jiang-Sheng Li and Wei Wei,* Visible-light-promoted acridine red catalyzed aerobic oxidative decarboxylative acylation of α-oxo-carboxylic acids with quinoxalin-2(1H)-ones, Org. Chem. Front. 2020, 7, 492–498. SCI 一区IF=5.456
[25] Ruisheng Liu, Qishun Liu, Haoran Meng, Hongyu Ding, Jindong Hao,Zhongyin Ji, Huilan Yue * and Wei Wei*，Metal-free visible-light-induced aerobic oxidation of α-diazoesters leading to α-ketoesters in air, Org. Chem. Front., 2021, 8, 1970. SCI 一区IF=5.456
[26] Na Meng, Leilei Wang, Qishun Liu, Qinyu Li, Yufen Lv,* Huilan Yue,* Xiaojuan Wang, and Wei Wei*，Metal-Free Trifluoroalkylation of Quinoxalin-2(1H)‑ones with Unactivated Alkenes and Langlois’ Reagent，J. Org. Chem. 2020, 85, 6888−6896 SCI 二区topIF=4.83
[27] Yufen Lv, Huanhuan Cui, Na Meng, Huilan Yue, Wei Wei, Recent advances in the application of sulfinic acids for the construction of sulfur-containing compounds, Chin. Chem. Lett. 2022, 33, 97–114 SCI一区IF=8.455
[28] Na Meng; Yufen Lv; Qishun Liu; Ruisheng Liu; Xiaohui Zhao*; Wei Wei*，Visible-light-induced three-component reaction of quinoxalin-2(1H)-ones, alkenes and CF3SO2Na leading to 3-trifluoroalkylated quinoxalin-2(1H)-ones, Chin. Chem. Lett. 2021, 32, 258-262，SCI一区IF=8.455
[29] Qishun Liu , Yufen Lv, Ruisheng Liu, Xiaohui Zhao*, Jiawen Wang, Wei Wei*, Catalyst- and additive-free selective sulfonylation/cyclization of 1,6- enynes with arylazo sulfones leading to sulfonylated g-butyrolactams, Chin. Chem. Lett. 2021, 32, 136-139 SCI一区IF=8.455
[30] Leilei Wang, Min Zhang, Yulong Zhang, Qishun Liu, Xiaohui Zhao*, Jiang-Sheng Li, Zidan Luo, Wei Wei,* Metal-free visible-light-induced oxidative cyclization reaction of 1,6-enynes and arylsulfinic acids leading to sulfonylated benzofurans, Chin. Chem. Lett. 2020, 31, 67–70. SCI一区IF=8.455
[31] Qiang Huang, Lei Zhu, Dong Yi*, Xiaohui Zhaoc*, and Wei Wei,* Silver-mediated aminophosphinoylation of propargyl alcohols witharomatic amines and H-phosphine oxides leading to α-aminophosphine oxides, Chin. Chem. Lett. 2020, 31, 373–376. SCI一区IF=8.455
[32] Qishun Liu, Fei Liu, Huilan Yue, Xiaohui Zhao,* Jiangsheng Li, and Wei Wei,* Photocatalyst-Free Visible Light-Induced Synthesis of β-OxoSulfones via Oxysulfonylation of Alkenes with Arylazo Sulfones and Dioxygen in Air, Adv. Synth. Catal. 2019, 361, 5277–5282 SCI 一区IF=5.48
[33] Pengli Bao, Huilan Yue, Na Meng, Xiaohui Zhao,* Jiangsheng Li, and Wei Wei,* Copper-Catalyzed Three-Component Reaction of Alkynes, TMSN3, and Ethers: Regiocontrollable Synthesis of N1 - and N2‑Oxyalkylated 1,2,3-Triazoles, Org. Lett. 2019, 21, 7218−7222.SCI 一区IF=6.03
[34] Qiang Huang, Kaikai Dong, Wenjing Bai, Dong Yi, Jian-Xin Ji,* and Wei Wei,* TEMPO-Catalyzed Aminophosphinoylation of Ethers via Tandem C(sp3)−H and C(sp3)−O Bond Cleavage, Org. Lett. 2019, 21, 3332−3336.SCI 一区IF=6.03
[35] Pengli Bao, Leilei Wang, Huilan Yue, Yun Shao, Jiangwei Wen, Daoshan Yang, Xiaohui Zhao, Hua Wang, and Wei Wei,* Metal-Free Catalytic Synthesis of Thiocarbamates Using Sodium Sulfinates as the Sulfur Source, J. Org. Chem. 2019, 84, 2976−2983. SCI 二区top
[36] Pengli Bao, Na Meng, Yufen Lv, Huilan Yue, Jiang-Sheng Li and Wei Wei,* Selective assembly of N1- and N2-alkylated 1,2,3- triazoles via copper-catalyzed decarboxylative cycloaddition of alkynyl carboxylic acids with ethers and azidotrimethylsilane, Org. Chem. Front. 2019, 6, 3983–3988.SCI 一区IF=5.155
[37] Wei Wei,* Pengli Bao, Huilan Yue,* Sitong Liu, Leilei Wang, Yudong Li, and Daoshan Yang, Visible-Light-Enabled Construction of Thiocarbamates from Isocyanides, Thiols, and Water at Room Temperature, Org. Lett. 2018, 20, 5291−5295.SCI 一区IF=6.03
[38] Wei Wei,* Leilei Wang, Pengli Bao, Yun Shao, Huilan Yue, Daoshan Yang, Xiaobo Yang, Xiaohui Zhao,* and Hua Wang, Metal-Free C(sp2)−H/N−H Cross-Dehydrogenative Coupling of Quinoxalinones with Aliphatic Amines under Visible-Light Photoredox Catalysis, Org. Lett. 2018, 20, 7125−7130.SCI 一区IF=6.03
[39] Wei Wei,* Leilei Wang, Huilan Yue,* Pengli Bao, Weiwei Liu, Changsong Hu, Daoshan Yang, and Hua Wang, Metal-Free Visible-Light-Induced C−H/C−H Cross-Dehydrogenative Coupling of Quinoxalin-2(H)-ones with Simple Ethers, ACS Sustainable Chem. Eng. 2018, 6, 17252−17257.SCI 一区IF=7.632
[40] Wei Wei,* Huanhuan Cui, Huilan Yue* and Daoshan Yang*, Visible-light-enabled oxyazidation of alkenes leading to α-azidoketones in air. Green Chem. 2018, 20, 3197–3202. SCI 一区IF=9.480
[41] Daoshan Yang, * Guoqing Li, Chengyu Xing, Wenwen Cui, Kexin Li and Wei Wei*, Metal- and photocatalyst-free visible-lightpromoted regioselective selenylation of coumarin derivatives via oxidation-induced C-H functionalization, Org. Chem. Front. 2018, 5, 2974-2979.SCI 一区IF=5.155
[42] Leilei Wang,# Huilan Yue,# Daoshan Yang, Huanhuan Cui, Minghui Zhu, Jinming Wang, Wei Wei,* Hua Wang*, Metal-free Oxidative Coupling of Aromatic alkenes with Thiols Leading to (E)-Vinyl sulfones. J. Org. Chem., 2017, 82, 6857-6864. SCI 二区topIF=9.480
[43] Wei Wei*, Huanhuan Cui, Daoshan Yang, Xiaoxia Liu, Chenglong He, Shicui Dai, Hua Wang*. Metal-free molecular iodine catalyzed direct sulfonylation of pyrazolones with sodium sulfinates leading to sulfonated pyrazoles at room temperature, Org. Chem. Front. 2017, 4, 26-30.SCI 一区IF=5.155
[44] Qiang Fu, Dong Yi, Zhijie Zhang, Wu Liang, Suyuan Chen, Lu Yang, Qiang Zhang,* Jianxin Ji and Wei Wei*, Copper-catalyzed aerobic oxidative coupling of ketones with P(O)–H compounds leading to β-ketophosphine oxides, Org. Chem. Front. 2017, 4, 1385-1389.SCI 一区IF=5.155
[45] Huanhuan Cui, Xiaoxia Liu, Wei Wei*, Daoshan Yang, Chenglong He, Tiantian Zhang, and Hua Wang*, Molecular iodine Mediated Difunctionalization of Alkenes with Nitriles and Thiols Leading to β-Acetamido Sulfides, J. Org. Chem. 2016, 81, 2252−2260 SCI 二区top IF=4.812
[46] Wei Wei, Jiangwei Wen, Daoshan Yang, Mengyuan Guo, Yingying Wang, Jinmao You, Hua Wang*, Direct and metal-free arylsulfonylation of alkynes with sulfonylhydrazides for the construction of 3-sulfonated coumarins, Chem Commun. 2015, 51, 768−771.SCI 一区IF=6.03
[47] Wei Wei, Chunli Liu, Daoshan Yang, Jiangwei Wen, Jinmao You, Hua Wang*. Metal Free Direct Construction of Sulfonamides via Iodine Mediated Coupling Reaction of Sodium Sulfinates and Amines at Room Temperature, Adv. Synth. Catal. 2015, 357, 987−992.SCI 一区IF=5.45
[48] Jiangwei Wen, Wei Wei,* Shengnan Xue, Daoshan Yang, Yu Lou, Chaoyang Gao, Hua Wang*, Metal-free Oxidative Spirocyclization of Alkynes with Sulfonylhydrazides leading to 3-Sulfonated Azaspiro[4,5]trienones, J. Org. Chem. 2015, 80, 4966−4972. SCI 二区topIF=4.812
[49] Chunli Liu#, Minghui Zhu#, Wei Wei*, Daoshan Yang, Hong Cui, Xiaoxia Liu, Hua Wang*, Metal-free direct difunctionalization of alkenes with I2O5 and P(O)-H compounds leading to β-iodophosphates, Org. Chem. Front. 2015, 2, 1356-1360.SCI 一区IF=5.155
[50] Wei Wei, Jiangwei Wen, Daoshan Yang, Juan Du, Jinmao You, Hua Wang, Catalyst-free direct arylsulfonylation of N-arylacrylamides with sulfinic acids: a convenient and efficient route to sulfonated oxindoles, Green Chem. 2014, 16, 2988-2991. SCI 一区IF=9.48
